Eptifibatide, Acetate

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China

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Telegraphic Transfer (T/T)

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1g

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Map-Har-Gly-Asp-Trp-Trp-Cys-NH2
Disulfide bridge Map1-Cys6
CAS [148031-34-9]
C35H49N11O9S2

Eptifibatide is a cyclic heptapeptide containing six amino acids and one mercaptopropionyl (des-amino cysteinyl) residue. An interchain disulfide bridge is formed between the cysteine amide and the mercaptopropionyl moieties. Chemically it is N 6 -(aminoiminomethyl)-N 2 -(3-mercapto-1-oxopropyl-L- lysylglycyl-L-a-aspartyl- L-tryptophyl-L -prolyl-L-cysteinamide, cyclic (1?)-disulfide. Eptifibatide binds to the platelet receptor glycoprotein (GP) IIb/IIIa of human platelets and inhibits platelet aggregation.

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